Dynamic Tyrosine Kinase-Regulated Signaling and Actin Polymerisation Mediate Aggregate Stability Under Shear
نویسندگان
چکیده
منابع مشابه
Dynamic tyrosine kinase-regulated signaling and actin polymerisation mediate aggregate stability under shear.
OBJECTIVE Aggregate formation on collagen at arteriolar rates of shear is mediated by coordinated signaling between tyrosine kinase-linked and G protein-coupled receptors. We have investigated the role of these receptors and the actin cytoskeleton in maintaining aggregate stability under shear. METHODS AND RESULTS Platelet aggregates are rapidly formed when blood is flowed over collagen at 10...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2008
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.108.167296